The death of 'Heroes' and 'Nashville' star Hayden Panettiere has taken a new turn. The DEA has joined the investigation, a preliminary autopsy found no signs of trauma, and a friend issued an enigmatic warning. Meanwhile, her final PETA campaign against animal captivity has been released, shedding light on her long battle with pain and addiction.

DEA Joins the Investigation

The investigation into the death of Hayden Panettiere, which occurred on Sunday, August 16 in Greenville, South Carolina, has taken a major turn. According to police sources cited by Page Six and TMZ, the U.S. Drug Enforcement Administration (DEA) has joined the team investigating the 36-year-old actress's death. Federal agents specializing in narcotics are now working alongside local police, suggesting that the overdose hypothesis is gaining strength.

This move mirrors the case of Matthew Perry, the 'Friends' actor, when the DEA also became involved in the investigation following his death in 2023. The presence of the federal agency does not confirm the cause of death, but it does indicate that authorities are looking into the origin of any substances the actress may have consumed.

What Was Found in the Apartment

The official report states that Zach Hickerson, brother of her boyfriend Brian Hickerson, found Panettiere's body. She was seated in a living room chair and unresponsive. Emergency services attempted to revive her for over 30 minutes, but she was pronounced dead at 2:32 PM.

At the scene, police found nine different medications and a Narcan device—a medication used to reverse opioid overdoses—on a mattress. Although the report does not specify what substances were in the bag of medications handed over by Brian Hickerson, the discovery of Narcan is a key clue for investigators.

The officer who wrote the report, identified as Matt Bryan, noted that Zach Hickerson appeared 'very upset,' while Brian Hickerson seemed in shock. He only reacted when he was told of her death, at which point he handed over the bag of medications.

“Don't trust her mother, from whom she was estranged, nor any of her abusers. She worked too hard and came too far to end up like this.”

Ruby Rose, actress and friend of Panettiere

Ruby Rose's Enigmatic Message

Actress Ruby Rose posted a lengthy message on her social media that raised alarms. After an initial tribute, Rose wrote again about her friend with unsettling words: “There are things that are wrong and scary out there.” She urged fans to be patient and not to trust Panettiere's mother or her “abusers”. This message, while lacking concrete details, reflects the tension surrounding the case.

Panettiere's mother, Lesley Vogel, had broken her silence days earlier, accusing Brian Hickerson of being present at the time of death and saying her daughter “lost her way.” The relationship between mother and daughter was distant, according to Vogel's statements to NBC News.

The Zebra That Changed Her Life

Infobae published a detailed report on the origin of the pain that followed Panettiere for over 20 years. At age 14, during the filming of “Racing Stripes” in South Africa, a zebra threw her to the ground. The accident caused a concussion, severe whiplash, and injuries to two vertebrae in her neck.

In her memoir “This Is Me: A Reckoning”, published in May 2026, the actress wrote: “I kept my mouth shut and endured the pain in my back and neck. More than 20 years later, these injuries still bother me.” Whenever the injury flared up, she turned to opioids.

Her dependence began earlier, at age 15, when she took so-called “happiness pills” to appear cheerful in interviews. Years later, postpartum depression after the birth of her daughter Kaya in 2014 led her to alcoholism. “I turned to wine, which led to an alcohol dependence. It was my way of surviving each day,” she confessed.

Panettiere's Final Campaign

The organization PETA released her last campaign on Tuesday, August 19, which the actress had filmed just two weeks before her death. In the piece, Panettiere appears naked inside a bathtub to denounce the confinement of dolphins and whales in marine parks. The image aims to depict what it would mean to spend an entire life confined to a tiny space, as these marine mammals do in captivity.

PETA explained that the campaign was in the works and they decided to launch it as a tribute to the actress's commitment to animal welfare. Panettiere was a dedicated activist for years, speaking out against dolphin hunting and the captivity of marine species.

The preliminary autopsy conducted by the Greenville County Medical Examiner's Office found no signs of trauma that could have contributed to her death. Toxicological results are still pending and will be crucial in determining the official cause of death.